NPS antibody (AA 70-89) (AbBy Fluor® 594)
-
- Target See all NPS Antibodies
- NPS (Neuropeptide S (NPS))
-
Binding Specificity
- AA 70-89
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This NPS antibody is conjugated to AbBy Fluor® 594
-
Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Neuropeptide S
- Isotype
- IgG
- Top Product
- Discover our top product NPS Primary Antibody
-
-
- Application Notes
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- NPS (Neuropeptide S (NPS))
- Alternative Name
- NPS/Neuropeptide S (NPS Products)
- Synonyms
- ENSMUSG00000073804 antibody, neuropeptide S antibody, NPS antibody, Nps antibody
- Background
-
Synonyms: NeuropeptideS, Neuropeptide-S, NPS, NPS_HUMAN.
Background: Neuropeptides are regulators of synaptic transmission and their effects are mediated by G-protein coupled receptors. NPS (Neuropeptide S) is a 20 amino acid peptide cleaved from a larger precursor that contains a hydrophobic signal peptide and proteolytic cleavage processing sites. The N-terminal residue of NPS is always a serine regardless of the species. NPS is predominantly found in the central nervous system and plays an important role regulating sleep/wake functions, locomotion, arousal/anxiety responses and food intake. NPS functions by binding and activating its receptor, NPSR, and increasing intracellular calcium levels thereby acting as an excitatory transmitter. In addition, NPS stimulates the hypothalamo-pituitary adrenal (HPA) axis via the release of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP). NPS and its receptor NPSR may also play a role in asthma pathogenesis.
- Gene ID
- 594857
-