LINGO1 antibody (AA 521-620) (AbBy Fluor® 594)
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- Target See all LINGO1 Antibodies
- LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))
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Binding Specificity
- AA 521-620
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LINGO1 antibody is conjugated to AbBy Fluor® 594
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Mouse, Rat
- Predicted Reactivity
- Human,Dog,Cow,Pig,Horse,Chicken
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Lingo-1
- Isotype
- IgG
- Top Product
- Discover our top product LINGO1 Primary Antibody
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- Application Notes
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))
- Alternative Name
- Lingo-1 (LINGO1 Products)
- Synonyms
- lern1 antibody, lrrn6a antibody, unq201 antibody, DKFZp459P0736 antibody, LERN1 antibody, LRRN6A antibody, UNQ201 antibody, 4930471K13Rik antibody, AV148400 antibody, LINGO-1 antibody, Lrrn6a antibody, leucine rich repeat and Ig domain containing 1 antibody, LINGO1 antibody, lingo1 antibody, Lingo1 antibody
- Background
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Synonyms: Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Leucine-rich repeat and immunoglobulin domain-containing protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A, LINGO1, LERN1, LRRN6A, UNQ201/PRO227
Background: Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).
- Gene ID
- 84894
- UniProt
- Q96FE5
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