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FOLR2 antibody

FOLR2 Reactivity: Human WB, FACS, IP, ICC Host: Mouse Monoclonal EM-35 unconjugated
Catalog No. ABIN2800693
  • Target See all FOLR2 Antibodies
    FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
    Reactivity
    • 51
    • 19
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 46
    • 8
    • 1
    Mouse
    Clonality
    • 45
    • 9
    • 1
    Monoclonal
    Conjugate
    • 27
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FOLR2 antibody is un-conjugated
    Application
    • 42
    • 29
    • 16
    • 11
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Specificity
    The mouse monoclonal antibody EM-35 recognizes an extracellular epitope on FOLR2, a 30-40 kDa cell surface protein serving as a receptor for folic acid.
    No Cross-Reactivity
    Mouse
    Cross-Reactivity (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Purity
    > 95 % (by SDS-PAGE)
    Immunogen
    BW5147alpha,beta- cells
    Clone
    EM-35
    Isotype
    IgG1
    Top Product
    Discover our top product FOLR2 Primary Antibody
  • Application Notes
    Western blotting: Non-reducing conditions.
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Target
    FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
    Alternative Name
    FOLR2 (FOLR2 Products)
    Synonyms
    FOLR2 antibody, BETA-HFR antibody, FBP antibody, FBP/PL-1 antibody, FR-BETA antibody, FR-P3 antibody, FBP2 antibody, Folbp-2 antibody, Folbp2 antibody, folate receptor 1 antibody, folate receptor beta antibody, folate receptor 2 (fetal) antibody, FOLR1 antibody, FOLR2 antibody, Folr2 antibody
    Background
    Folate receptor beta,FOLR2 (folate receptor beta) is a cell surface protein that was originally thought to be specific for placenta, but it can be also expressed in other tissues, including hematopoietic cells. Its expression is increased in malignant tissues. FOLR2 may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. FOLR2 is a marker for macrophages generated in the presence of M-CSF (M2), including M2-like tumor-associated macrophages, which exert potent immunosuppressive functions within the tumor environment, but not GM-CSF (M1), and whose expression correlates with increased folate uptake ability.,Folate receptor beta, FBP, FR-P3, FR-BETA, BETA-HFR, FBP/PL-1
    Gene ID
    2350
    UniProt
    P14207
    Pathways
    Dicarboxylic Acid Transport
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