GSK3 beta antibody (N-Term)

Catalog No. ABIN2798780

Product Details anti-GSK3 beta Antibody

Target: GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))

Binding Specificity: AA 30-59, N-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSK3 beta antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: Rabbit Anti-Mouse Mouse Gsk3b (N-term) Antibody

Immunogen: This Mouse Gsk3b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of mouse Gsk3b.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Mouse Gsk3b Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for GSK3 beta

Target: GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))

Alternative Name: Gsk3b (GSK3b Products)

Synonyms: GSK3 antibody, GSK-3 antibody, C86142 antibody, GSK-3beta antibody, 7330414F15Rik antibody, 8430431H08Rik antibody, GSK3beta antibody, fk80d11 antibody, GSK-3[b] antibody, wu:fb68h05 antibody, wu:fk80d11 antibody, gsk-3 antibody, gsk3 antibody, gsk3-beta antibody, gsk3beta antibody, xgsk-3 antibody, glycogen synthase kinase 3 beta antibody, glycogen synthase kinase 3 beta L homeolog antibody, GSK3B antibody, Gsk3b antibody, gsk3b antibody, gsk3b.L antibody

Background:

Target Description: Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. May phosphorylate MUC1 and decrease the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1 (By similarity).

Gene Symbol: Gsk3b

Molecular Weight: 46710 Da

Gene ID: 56637

UniProt: Q9WV60

Pathways: WNT Signaling, Hedgehog Signaling, Fc-epsilon Receptor Signaling Pathway, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagy, BCR Signaling, Warburg Effect