TMEM43 antibody (Center)
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- Target See all TMEM43 Antibodies
- TMEM43 (Transmembrane Protein 43 (TMEM43))
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Binding Specificity
- AA 195-223, Center
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TMEM43 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Western Blotting (WB)
- Purpose
- Rabbit Anti-Human TMEM43 (Center) Antibody
- Immunogen
- This TMEM43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of human TMEM43.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product TMEM43 Primary Antibody
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- Application Notes
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50TMEM43 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Target
- TMEM43 (Transmembrane Protein 43 (TMEM43))
- Alternative Name
- TMEM43 (TMEM43 Products)
- Synonyms
- zgc:85946 antibody, ARVC5 antibody, ARVD5 antibody, EDMD7 antibody, LUMA antibody, 1200015A22Rik antibody, transmembrane protein 43 antibody, TMEM43 antibody, tmem43 antibody, Tmem43 antibody
- Background
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Target Description: This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.
Gene Symbol: TMEM43
- Molecular Weight
- 44876 Da
- Gene ID
- 79188
- UniProt
- Q9BTV4
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