KDELR1 antibody (C-Term)
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- Target See all KDELR1 Antibodies
- KDELR1 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))
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Binding Specificity
- AA 185-211, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KDELR1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit Anti-Human KDELR1 (C-term) Antibody
- Immunogen
- This KDELR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-211 amino acids from the C-terminal region of human KDELR1.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product KDELR1 Primary Antibody
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- Application Notes
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Western Blot
Recommended Dilutions
WB: 1:1000KDELR1 Antibody (C-term) . - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.470 mg/mL
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Target
- KDELR1 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))
- Alternative Name
- KDELR1 (KDELR1 Products)
- Synonyms
- ERD2 antibody, ERD2.1 antibody, HDEL antibody, PM23 antibody, 8030486F04Rik antibody, AW215843 antibody, Erd2.1 antibody, KDEL endoplasmic reticulum protein retention receptor 1 antibody, KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 antibody, KDELR1 antibody, Kdelr1 antibody
- Background
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Target Description: Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product.
Gene Symbol: KDELR1
- Molecular Weight
- 24542 Da
- Gene ID
- 10945
- UniProt
- P24390
- Pathways
- Maintenance of Protein Location
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