Helical Factor antibody (C-Term)
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- Target See all Helical Factor (HF) products
- Helical Factor (HF)
- Binding Specificity
- AA 135-164, C-Term
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Helical Factor antibody is un-conjugated
- Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purpose
- Rabbit Anti-Mouse Mouse DHFR (C-term) Antibody
- Immunogen
- This Mouse DHFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the C-terminal region of mouse DHFR.
- Isotype
- Ig Fraction
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- Application Notes
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100Western blot analysis of DHFR antibody (C-term) with the DHFR gene. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2.0 mg/mL
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Target
- Helical Factor (HF)
- Alternative Name
- DHF (HF Products)
- Background
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Target Description: Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.
Gene Symbol: Dhfr
- Molecular Weight
- 21606 Da
- Gene ID
- 13361
- UniProt
- P00375
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