Caveolin-1 antibody (N-Term)
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- Target See all Caveolin-1 (CAV1) Antibodies
- Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Mouse, Dog, Pig, Cow, Rabbit, Sheep, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Caveolin-1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- SGGKYVDSEG HLYTVPIREQ GNIYKPNNKA MADELSEKQV YDAHTKEIDL
- Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
- Predicted Reactivity
- Cow: 80%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 80%, Rabbit: 86%, Rat: 86%, Sheep: 80%
- Characteristics
- This is a rabbit polyclonal antibody against CAV1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CAV1
- Top Product
- Discover our top product CAV1 Primary Antibody
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- Application Notes
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WB Suggested Anti-CAV1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:62500
Positive Control: Human Liver.
Optimal working dilutions should be determined experimentally by the investigator. - Comment
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Antigen size: 178 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
- Alternative Name
- Caveolin-1 (CAV1 Products)
- Synonyms
- fc07c04 antibody, wu:fc07c04 antibody, Cav-1 antibody, bscl3 antibody, cav1 antibody, cav1a antibody, cgl3 antibody, vip21 antibody, cav1b antibody, caveolin-1 antibody, cav antibody, mstp085 antibody, Caveolin-1 antibody, CAV1 antibody, cav-1 antibody, Cav antibody, caveolin 1 antibody, BSCL3 antibody, CGL3 antibody, MSTP085 antibody, PPH3 antibody, VIP21 antibody, caveolin 1 antibody, caveolin 1 L homeolog antibody, caveolin 1 S homeolog antibody, caveolin 1, caveolae protein antibody, caveolin 1, caveolae protein, 22kDa antibody, Caveolin antibody, cav1 antibody, cav1.L antibody, cav1.S antibody, CAV1 antibody, Cav1 antibody, cav-1 antibody
- Background
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The scaffolding protein CAV1 is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CAV, MSTP085, VIP21, CGL3, BSCL3
Protein Interaction Partner: TFRC, ABCC1, UBC, RPA3, ATG5, ATG12, RPA2, RPA1, PTGIS, EGFR, VCP, UFD1L, PTGS2, PTGS1, ESR1, DERL1, VIMP, ATP4A, CAV2, GLIPR2, KDR, PROCR, F2R, BID, NOS3, HSP90AA1, FAS, ACTB, MALL, NF1, LRP6, KCNMA1, BMPR2, BMPR1A, AXIN1, PPP2CA, MCL1, ITPR3, ID1, TENC1
Protein Size: 178 - Molecular Weight
- 20 kDa
- Gene ID
- 857
- NCBI Accession
- NM_001753, NP_001744
- UniProt
- Q03135
- Pathways
- Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals
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