LMO2 antibody (N-Term)

Catalog No. ABIN2792668

Product Details anti-LMO2 Antibody

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Binding Specificity: N-Term

Reactivity: Mouse, Rat, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMO2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GGGARAPEGV RAPAAGQPRA TKGAPPPPGT PPPSPMSSAI ERKSLDPSEE

Cross-Reactivity: Cow (Bovine), Chicken, Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against LMO2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LMO2

Application Details

Application Notes: WB Suggested Anti-LMO2 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: Human kidney.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 158 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LMO2

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Alternative Name: Rhombotin-2 (LMO2 Products)

Synonyms: Rbtn-2 antibody, Rbtn2 antibody, Rhom-2 antibody, Ttg2 antibody, RBTN2 antibody, RBTNL1 antibody, RHOM2 antibody, TTG2 antibody, wu:fc83a08 antibody, zgc:111930 antibody, LMO-2 antibody, lmo2-A antibody, xlmo2 antibody, rhombotin-2 antibody, LIM domain only 2 antibody, LIM domain only 2 (rhombotin-like 1) antibody, LIM domain only 2 S homeolog antibody, lmo2 antibody, LMO2 antibody, Lmo2 antibody, lmo2.S antibody

Background: LMO2 acts with TAL1/SCL to regulate red blood cell development. LMO2 also acts with LDB1 to maintain erythroid precursors in an immature state.LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: RBTN2, RBTNL1, RHOM2, TTG2
Protein Interaction Partner: ADAMTSL4, MBIP, HOOK1, TFPT, NOTCH2NL, KRTAP10-7, CCDC36, NUTM1, SPERT, FAM154A, CLHC1, KRT40, SSX2IP, CMTM5, MRFAP1L1, IFT43, C1orf94, LZTS2, TSC22D4, DBF4B, CCDC33, RINT1, NIF3L1, TRIM54, AGTRAP, ZFP64, BANP, STAT3, STAT1, SOX5, SKP1, ROCK1, REL, PRKG1,
Protein Size: 158

Molecular Weight: 18 kDa

Gene ID: 4005

NCBI Accession: NM_005574, NP_005565

UniProt: P25791

Pathways: Chromatin Binding