Id2 antibody (Middle Region)

Catalog No. ABIN2792664

Product Details anti-Id2 Antibody

Target: Id2 (Inhibitor of DNA Binding 2 (Id2))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Id2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Sequence: TIVSLHHQRP GQNQASRTPL TTLNTDISIL SLQASEFPSE LMSNDSKALC

Cross-Reactivity: Cow (Bovine), Chicken, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)

Predicted Reactivity: Cow: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ID2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ID2

Application Details

Application Notes: WB Suggested Anti-ID2 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: Human Thymus.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 134 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Id2

Target: Id2 (Inhibitor of DNA Binding 2 (Id2))

Alternative Name: ID2 / BHLHB26 (Id2 Products)

Synonyms: AI255428 antibody, C78922 antibody, Idb2 antibody, bHLHb26 antibody, Ac2-300 antibody, GIG8 antibody, ID2A antibody, ID2H antibody, XId2 antibody, id2-A antibody, inhibitor of DNA binding 2 antibody, inhibitor of DNA binding 2, HLH protein antibody, inhibitor of DNA binding 2 L homeolog antibody, Id2 antibody, ID2 antibody, id2.L antibody

Background: ID2 belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation.The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GIG8, ID2A, ID2H, MGC26389, bHLHb26
Protein Interaction Partner: ASB4, UBC, SUV39H2, PRMT6, KDM1A, SUV39H1, TCF12, TCF3, TSTA3, MAPK8, ID2, HSPA5, RBL2, RBL1, RB1, CDK2, USP1, MAPK3, MAPK1, E2F4, SIN3A, GATA4, NKX2-5, LRIF1, PPP1CA, RBM48, NEDD9, UNC119, MSC, TCF4, ELK3, ELK4, ELK1, PAX8, PAX5, PAX2, MYF6, MYF5, MYOG,
Protein Size: 134

Molecular Weight: 15 kDa

Gene ID: 3398

NCBI Accession: NM_002166, NP_002157

UniProt: Q02363