CSDA antibody (N-Term)

Catalog No. ABIN184337

Product Details anti-CSDA Antibody

Target: CSDA (Cold Shock Domain Protein A (CSDA))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Pig, Rat, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSDA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AHVAGNPGGD AAPAATGTAA AASLAAAAGS EDAEKKVLAT KVLGTVKWFN

Cross-Reactivity: Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 84%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CSDA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CSDA

Application Details

Application Notes: WB Suggested Anti-CSDA Antibody Titration: 1 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 372 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CSDA

Target: CSDA (Cold Shock Domain Protein A (CSDA))

Alternative Name: DNA-binding protein A (CSDA Products)

Background: Human DNA-binding protein (dbpA) is a member of a Y-box binding protein family containing a cold shock domain. The increased expression of Y box binding proteins in somatic cells is associated with cell proliferation and transformation.
Alias Symbols: DBPA, CSDA1, ZONAB
Protein Interaction Partner: CEP76, CEP250, UBC, SUZ12, RNF2, EZH2, BMI1, C14orf166, RTCB, NELFB, MACF1, IGF2BP3, EIF5B, MAP7, EIF2B2, EIF2B3, RFC4, PTBP1, NMT1, MRE11A, ILF2, HNRNPU, DHX9, DDX1, CSRP1, ABCF1, PARK2, SRPK3, TARDBP, ICAM1, IGSF8, HDAC11, PAN2, IL7R, IFIT3, IFIT2, ESR1
Protein Size: 372

Molecular Weight: 40 kDa

Gene ID: 8531

NCBI Accession: NM_003651, NP_003642

UniProt: P16989

Pathways: Negative Regulation of intrinsic apoptotic Signaling