YY1 antibody (Middle Region)

Catalog No. ABIN2792643

Product Details anti-YY1 Antibody

Target: YY1 (YY1 Transcription Factor (YY1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YY1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GADPGNKKWE QKQVQIKTLE GEFSVTMWSS DEKKDIDHET VVEEQIIGEN

Cross-Reactivity: Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Cow: 92%, Dog: 92%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against YY1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human YY1

Application Details

Application Notes: WB Suggested Anti-YY1 Antibody Titration: 0.2-1 µg/mL
Positive Control: Human Thymus.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 414 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for YY1

Target: YY1 (YY1 Transcription Factor (YY1))

Alternative Name: YY1 (YY1 Products)

Background: YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.
Alias Symbols: DELTA, NF-E1, UCRBP, INO80S, YIN-YANG-1
Protein Interaction Partner: HDAC1, SMURF2, UBC, SHFM1, RNF2, BMI1, SUZ12, RYBP, GABPB1, GABPA, PCGF2, RING1, EP300, LAMC2, SPRY1, SLC39A7, NR1H2, TESK1, RAF1, NFKB1, GRN, CRKL, ARRB1, SP1, WDHD1, ZNF24, NHP2L1, NCL, ZNF830, APP, ZNF638, EED, SMAD3, SMAD2, EZH2, SUMO1, SUMO3, INO80E,
Protein Size: 414

Molecular Weight: 45 kDa

Gene ID: 7528

NCBI Accession: NM_003403, NP_003394

UniProt: P25490