TAF1A antibody (C-Term)
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- Target See all TAF1A Antibodies
- TAF1A (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, A, 48kDa (TAF1A))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Mouse, Horse, Rabbit, Pig, Dog, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TAF1A antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- CEKAFVAGLL LGKGCRYFRY ILKQDHQILG KKIKRMKRSV KKYSIVNPRL
- Cross-Reactivity
- Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
- Predicted Reactivity
- Cow: 78%, Dog: 85%, Horse: 85%, Human: 100%, Mouse: 85%, Pig: 85%, Rabbit: 85%, Rat: 85%
- Characteristics
- This is a rabbit polyclonal antibody against TAF1A. It was validated on Western Blot using a cell lysate as a positive control.
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human TAF1A
- Top Product
- Discover our top product TAF1A Primary Antibody
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- Application Notes
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WB Suggested Anti-TAF1A Antibody Titration: 0.2-1 µg/mL
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Comment
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Antigen size: 336 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Genomic localization of the human genes TAF1A, TAF1B and TAF1C, encoding TAF(I)48, TAF(I)63 and TAF(I)110 subunits of class I general transcription initiation factor SL1." in: Cytogenetics and cell genetics, Vol. 89, Issue 1-2, pp. 133-6, (2000) (PubMed).
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Genomic localization of the human genes TAF1A, TAF1B and TAF1C, encoding TAF(I)48, TAF(I)63 and TAF(I)110 subunits of class I general transcription initiation factor SL1." in: Cytogenetics and cell genetics, Vol. 89, Issue 1-2, pp. 133-6, (2000) (PubMed).
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- Target
- TAF1A (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, A, 48kDa (TAF1A))
- Alternative Name
- TAF1A (TAF1A Products)
- Synonyms
- TAFI48 antibody, mTAFI48 antibody, MGC:17061 antibody, RAFI48 antibody, SL1 antibody, TATA-box binding protein associated factor, RNA polymerase I, A antibody, TATA-box binding protein associated factor, RNA polymerase I subunit A antibody, Taf1a antibody, TAF1A antibody
- Background
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Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1A encodes the smallest SL1-specific TAF.
Alias Symbols: SL1, RAFI48, TAFI48, MGC:17061
Protein Interaction Partner: C11orf57, JMJD6, TBP, Taf1c, Taf1b, BKRF1, UBC, TAF12, TAF1D, HIST1H4A, HIST1H3A, HIST2H2BE, HIST2H2AC, ESR1, SET, TAF1A, RUNX2, TP53, CD3EAP, HIST4H4, HIST3H3, ANP32A, UBTF, RRN3, MYC,
Protein Size: 336 - Molecular Weight
- 40 kDa
- Gene ID
- 9015
- NCBI Accession
- NM_139352, NP_647603
- UniProt
- Q9NWA1
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