LYL1 antibody (N-Term)
(1 reference)-
- Target See all LYL1 Antibodies
- LYL1
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Binding Specificity
- N-Term
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Reactivity
- Human, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LYL1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ASPGPPQVEE VGHRGGSSPP RLPPGVPVIS LGHSRPPGVA MPTTELGTLR
- Cross-Reactivity
- Human
- Predicted Reactivity
- Human: 100%, Pig: 92%
- Characteristics
- This is a rabbit polyclonal antibody against LYL1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human LYL1
- Top Product
- Discover our top product LYL1 Primary Antibody
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anti-LYL1 (LYL1) (AA 1-280) antibody
LYL1 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-LYL1 (LYL1) (AA 212-244) antibodyLYL1 Reactivity: Human WB Host: Rabbit Polyclonal RB54126 unconjugated
anti-LYL1 (LYL1) (AA 35-84) antibodyLYL1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
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WB Suggested Anti-LYL1 Antibody Titration: 0.2-1 µg/mL
Positive Control: 721_B cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Comment
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Antigen size: 280 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Lyl1 interacts with CREB1 and alters expression of CREB1 target genes." in: Biochimica et biophysica acta, Vol. 1783, Issue 3, pp. 503-17, (2008) (PubMed).
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: "Lyl1 interacts with CREB1 and alters expression of CREB1 target genes." in: Biochimica et biophysica acta, Vol. 1783, Issue 3, pp. 503-17, (2008) (PubMed).
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- Target
- LYL1
- Alternative Name
- LYL1 (LYL1 Products)
- Synonyms
- bHLHa18 antibody, Lyl-1 antibody, LYL1, basic helix-loop-helix family member antibody, lymphoblastomic leukemia 1 antibody, LYL1 antibody, Lyl1 antibody
- Background
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LYL1 contains 1 basic helix-loop-helix (bHLH) domain. A chromosomal aberration, translocation t (7,19)(q35,p13) with TCRB, involving LYL1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL).
Alias Symbols: bHLHa18
Protein Interaction Partner: TAL1, TRIM33, DRG1, LMO1, LMO2, NFKB1, TCF3, NFKBIA, TCF4,
Protein Size: 280 - Molecular Weight
- 30 kDa
- Gene ID
- 4066
- NCBI Accession
- NM_005583, NP_005574
- UniProt
- P12980
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