NFYC antibody (C-Term)

Catalog No. ABIN2792552

Product Details anti-NFYC Antibody

Target: NFYC (Nuclear Transcription Factor Y, gamma (NFYC))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFYC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MTSLSPLHPS QQLYQIQQVT MPAGQDLAQP MFIQSANQPS DGQAPQVTGD

Cross-Reactivity: Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 85%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against NFYC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NFYC

Application Details

Application Notes: WB Suggested Anti-NFYC Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 458 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NFYC

Target: NFYC (Nuclear Transcription Factor Y, gamma (NFYC))

Alternative Name: NFYC (NFYC Products)

Synonyms: CBF-C antibody, CBFC antibody, H1TF2A antibody, HAP5 antibody, HSM antibody, NF-YC antibody, fb98f01 antibody, wu:fb98f01 antibody, zgc:55514 antibody, cbf-c antibody, cbfc antibody, h1tf2a antibody, hap5 antibody, hsm antibody, nf-yc antibody, NFYC antibody, Nfyc antibody, nuclear transcription factor Y subunit gamma antibody, nuclear transcription factor Y, gamma antibody, nuclear transcription factor Y subunit gamma L homeolog antibody, nuclear transcription factor-Y gamma antibody, nuclear Y/CCAAT-box binding factor C subunit NF-YC antibody, NFYC antibody, nfyc antibody, nfyc.L antibody, Nfyc antibody

Background: NFYC is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. NFYC forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity.
Alias Symbols: HSM, CBFC, HAP5, CBF-C, NF-YC, H1TF2A
Protein Interaction Partner: NFYA, CDK2, UBC, SNX2, NFYB, Cebpb, ELAVL1, GAPDH, KAT2B, TP73, TAF12, TAF11, TAF6, TBPL2, TRIM27, HDAC1, KIAA2018, ARID2, GLTSCR1, GLTSCR1L, ZDHHC17, CIC, POGZ, ATF6, ADNP2, LMO4, SREBF2, SP1, DR1, CSN2, DST, SMAD3, SMAD2, ATF6B, MYC, TBP,
Protein Size: 458

Molecular Weight: 50 kDa

Gene ID: 4802

NCBI Accession: NM_001142587

UniProt: Q13952

Pathways: Regulation of Lipid Metabolism by PPARalpha