TAL1 antibody (C-Term)

Catalog No. ABIN184276

Product Details anti-TAL1 Antibody

Target: TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QDVLSPNSSC GSSLDGAASP DSYTEEPAPK HTARSLHPAM LPAADGAGPR

Cross-Reactivity: Dog (Canine), Human

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against TAL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TAL1

Application Details

Application Notes: WB Suggested Anti-TAL1 Antibody Titration: 1.25 µg/mL
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 331 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TAL1 antibody (ABIN184276)

Akgül, Lin, Ou Yang, Chen, Lu, Chen, Kikuchi, Chen, Tu: "Garlic accelerates red blood cell turnover and splenic erythropoietic gene expression in mice: evidence for erythropoietin-independent erythropoiesis." in: PLoS ONE, Vol. 5, Issue 12, pp. e15358, (2011) (PubMed).

Target Details for TAL1

Target: TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))

Alternative Name: TAL1 (TAL1 Products)

Background: The tal-1 proto-oncogene encodes a helix-loop-helix DNA-binding protein that has been implicated in the formation of T cell acute lymphoblastic leukemia (T-ALL).
Alias Symbols: SCL, TCL5, tal-1, bHLHa17
Protein Interaction Partner: ELSPBP1, SIN3A, KAT2B, EP300, HOXB9, DRG1, CHD3, ZHX1, STUB1, UBC, RB1, SSBP2, SSBP3, RCOR1, KDM1A, LDB1, TCF12, TCF3, RBBP7, LYL1, HDAC2, HDAC1, CHD4, CBFA2T3, RUNX1, SUPT16H, TAL1, CDK9, TRIM33, SUV39H1, SATB1, TRIM27, NCAPG2, MAPK3, SP1, LMO1, LMO2, GA
Protein Size: 331

Molecular Weight: 34 kDa

Gene ID: 6886

NCBI Accession: NM_003189, NP_003180

UniProt: P17542

Pathways: Stem Cell Maintenance