Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

PRDM1 antibody (Middle Region)

PRDM1 Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Horse, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2792524
  • Target See all PRDM1 Antibodies
    PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
    Binding Specificity
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 62
    • 16
    • 11
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Horse, Guinea Pig
    Host
    • 40
    • 23
    • 3
    • 1
    Rabbit
    Clonality
    • 45
    • 22
    Polyclonal
    Conjugate
    • 45
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRDM1 antibody is un-conjugated
    Application
    • 51
    • 36
    • 13
    • 11
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    VEDDISVISV VEKEILAVVR KEKEETGLKV SLQRNMGNGL LSSGCSLYES
    Cross-Reactivity
    Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 84%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 92%, Rat: 92%
    Characteristics
    This is a rabbit polyclonal antibody against PRDM1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human PRDM1
    Top Product
    Discover our top product PRDM1 Primary Antibody
  • Application Notes
    WB Suggested Anti-PRDM1 Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:62500
    Positive Control: SH-SYSY cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 691 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Arulanandam, Batenchuk, Angarita, Ottolino-Perry, Cousineau, Mottashed, Burgess, Falls, De Silva, Tsang, Howe, Bourgeois-Daigneault, Conrad, Daneshmand, Breitbach, Kirn, Raptis, Sad, Atkins, Huh et al.: "VEGF-Mediated Induction of PRD1-BF1/Blimp1 Expression Sensitizes Tumor Vasculature to Oncolytic Virus Infection. ..." in: Cancer cell, Vol. 28, Issue 2, pp. 210-24, (2015) (PubMed).

  • Target
    PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
    Alternative Name
    PRDM1 / BLIMP1 (PRDM1 Products)
    Synonyms
    GB11750 antibody, CG5249 antibody, Dmel\\CG5249 antibody, blimp-1 antibody, dBlimp-1 antibody, dBlimp1 antibody, Blimp-1 antibody, Blimp1 antibody, nrd antibody, prdm1 antibody, ubo antibody, wu:fb99c12 antibody, zgc:91885 antibody, MGC52536 antibody, PRDM1 antibody, blimp1 antibody, xblimp1 antibody, prdi-bf1 antibody, BLIMP1 antibody, PRDI-BF1 antibody, ZNFPR1A1 antibody, PR/SET domain 1 antibody, probable serine/threonine-protein kinase DDB_G0282963 antibody, CG5249 gene product from transcript CG5249-RF antibody, blimp-1 antibody, PR domain containing 1a, with ZNF domain antibody, PR domain 1 S homeolog antibody, B lymphocyte induced maturation protein 1 antibody, PR domain 1 antibody, PR domain containing 1, with ZNF domain antibody, PRDM1 antibody, LOC408295 antibody, Blimp-1 antibody, CpipJ_CPIJ007425 antibody, prdm1a antibody, prdm1.S antibody, prdm1 antibody, Prdm1 antibody
    Background
    PRDM1 is a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
    Alias Symbols: BLIMP1, MGC118922, MGC118923, MGC118924, MGC118925, PRDI-BF1
    Protein Interaction Partner: PRMT5, SENP1, EHMT2, PIAS1, SUMO1, IRF2, IRF1, HDAC2, HDAC1, HIST1H1A, MS4A1, HSP90AA1, ATXN1, ELAVL1, KDM1A, IRF4, TLE2, TLE1, AES, PRMT7, HIST2H3A,
    Protein Size: 691
    Molecular Weight
    77 kDa
    Gene ID
    639
    NCBI Accession
    NM_182907, NP_878911
    UniProt
    Q86WM7
    Pathways
    Regulation of Muscle Cell Differentiation
You are here:
Support