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VEGFR2/CD309 antibody (N-Term)

Name: VEGFR2/CD309 antibody (N-Term)
SKU: ABIN2792307
Price: 483.54 USD
Availability: InStock

VEGFR2 Reactivity: Human, Pig, Dog, Horse, Cow WB, IHC Host: Rabbit Polyclonal unconjugated

WB Suggested Anti-KDR Antibody Titration: 0. (VEGFR2/CD309 antibody (N-Term))

Image no. 1 for anti-VEGF Receptor 2 (VEGFR2) (N-Term) antibody (ABIN2792307) (VEGFR2/CD309 antibody (N-Term))

Researcher: Department of Pathology, Hospital de Carabineros de Chile, Santiago, ChileApplication: IHCSpecies+tissue/cell type: Control-Human Placenta, Sample-Human colorectal cancer Primary Antibody dilution: 1:100Secondary Antibody: Biotinylated pig anti-rabbit+streptavidin-HRP (VEGFR2/CD309 antibody (N-Term))

IHC

KDR in endothelial cells in blood vessels in placenta was detected using HRP/AEC red color stain. (VEGFR2/CD309 antibody (N-Term))

IHC

4 images

Catalog No. ABIN2792307

Datasheet as PDF

Target See all VEGFR2/CD309 (VEGFR2) Antibodies

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
Binding Specificity
37

34

27

23

20

16

11

10

10

10

8

6

5

5

5

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reactivity
279

174

124

8

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1
Human, Pig, Dog, Horse, Cow
Host
266

52

15

1

1
Rabbit
Compatible Secondaries
Clonality
258

77
Polyclonal
Conjugate
156

28

17

10

10

7

7

7

7

7

7

6

5

5

5

5

5

5

5

5

5

5

5

2

2

1

1

1

1

1

1

1
This VEGFR2/CD309 antibody is un-conjugated
Application
206

111

89

69

62

22

22

18

13

13

11

9

7

7

7

4

2

2

1
Western Blotting (WB), Immunohistochemistry (IHC)

Sequence

LNVGIDFNWE YPSSKHQHKK LVNRDLKTQS GSEMKKFLST LTIDGVTRSD

Predicted Reactivity

Cow: 86%, Dog: 100%, Horse: 100%, Human: 100%, Pig: 100%

Characteristics

This is a rabbit polyclonal antibody against KDR. It was validated on Western Blot using a cell lysate as a positive control.

Purification

Affinity Purified

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human KDR

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Application Notes

Optimal working dilutions should be determined experimentally by the investigator.

Comment

Antigen size: 1356 AA

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Alternative Name

KDR (VEGFR2 Products)

Background

KDR is the receptor for VEGF or VEGFC. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Alias Symbols: CD309, FLK1, VEGFR, VEGFR2
Protein Interaction Partner: FBXO25, VEGFA, MYO1C, CAV1, NPM1, EPN1, SRC, CBL, IQGAP1, UBC, CSNK1D, FBXW11, BTRC, CUL1, AIMP2, SHC2, SYNGAP1, ACP1, ATR, FRS2, SH2D2A, DNM2, NRP1, VEGFC, GRB10, CDH5, GNAQ, SHC1, STAT1, NCK1, SHB, PLCG2, P2RY2, BMX, FIGF, KDR, TIMP3, PTPN6, PTPN11, ITG
Protein Size: 1356

Molecular Weight

151 kDa

Gene ID

3791

NCBI Accession

NM_002253, NP_002244

UniProt

P35968

Pathways

RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling