CHRNA3 antibody (N-Term)

Catalog No. ABIN2792247

Product Details anti-CHRNA3 Antibody

Target: CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LPVARASEAE HRLFERLFED YNEIIRPVAN VSDPVIIHFE VSMSQLVKVD

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against CHRNA3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNA3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 505 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHRNA3

Target: CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))

Alternative Name: CHRNA3 (CHRNA3 Products)

Synonyms: LNCR2 antibody, NACHRA3 antibody, PAOD2 antibody, (a)3 antibody, A730007P14Rik antibody, Acra-3 antibody, Acra3 antibody, cholinergic receptor nicotinic alpha 3 subunit antibody, cholinergic receptor, nicotinic, alpha polypeptide 3 antibody, CHRNA3 antibody, Chrna3 antibody

Background: The CHRNA3 subunit is expressed in the soma of the majority of pyramidal cells, with the most alpha 3 immunoreactivity observed in CA2-4 and entorhinal cortex and relatively less in CA1 and subicular pyramidal cell soma.
Alias Symbols: LNCR2, PAOD2, NACHRA3
Protein Interaction Partner: Ubqln1, CHRNB4,
Protein Size: 505

Molecular Weight: 57 kDa

Gene ID: 1136

NCBI Accession: NM_000743, NP_000734

UniProt: P32297

Pathways: Synaptic Membrane