CCL18 antibody (Middle Region)
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- Target See all CCL18 Antibodies
- CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CCL18 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- PQKFIVDYSE TSPQCPKPGV ILLTKRGRQI CADPNKKWVQ KYISDLKLNA
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against CCL18. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CCL18
- Top Product
- Discover our top product CCL18 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 89 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Eosinophils and monocytes produce pulmonary and activation-regulated chemokine, which activates cultured monocytes/macrophages." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 286, Issue 3, pp. L494-501, (2004) (PubMed).
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Eosinophils and monocytes produce pulmonary and activation-regulated chemokine, which activates cultured monocytes/macrophages." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 286, Issue 3, pp. L494-501, (2004) (PubMed).
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- Target
- CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))
- Alternative Name
- CCL18 (CCL18 Products)
- Synonyms
- H7AP1 antibody, PARC antibody, RP3-330M21.2 antibody, AMAC-1 antibody, AMAC1 antibody, CKb7 antibody, DC-CK1 antibody, DCCK1 antibody, MIP-4 antibody, SCYA18 antibody, cullin 9 antibody, C-C motif chemokine ligand 18 antibody, CUL9 antibody, CCL18 antibody
- Background
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CCL18 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by CCL18 displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses.
Alias Symbols: CKb7, PARC, AMAC1, DCCK1, MIP-4, AMAC-1, DC-CK1, SCYA18
Protein Interaction Partner: C14orf1, UNC119, CRMP1, TLE1, TP53, EEF1A1,
Protein Size: 89 - Molecular Weight
- 10 kDa
- Gene ID
- 6362
- NCBI Accession
- NM_002988, NP_002979
- UniProt
- P55774
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