Cullin 1 antibody (C-Term)

Catalog No. ABIN184175

Product Details anti-Cullin 1 Antibody

Target: Cullin 1 (CUL1)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HQQLLGEVLT QLSSRFKPRV PVIKKCIDIL IEKEYLERVD GEKDTYSYLA

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CUL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CUL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 776 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cullin 1

Target: Cullin 1 (CUL1)

Alternative Name: CUL1 (CUL1 Products)

Background: Cul1 may contribute to catalysis through the positioning of the substrate and the ubiquitin-conjugating enzyme
Protein Interaction Partner: CDC25A, RBX1, UBE2L6, BTRC, CDT1, NABP2, NEDD8, FBXW5, FBXW4, FBXL5, FBXW11, COPS5, COPS6, SKP2, BPLF1, UBE2F, FBXW7, UBE2D1, UBC, CDCA3, DAB2IP, SUMO2, FBXO31, FBXO10, FBXO2, FBXO46, FBXO18, FBXO11, FBXO4, CCNF, UBE2M, CAND1, DCUN1D3, DCUN1D2, DCUN1D1, S
Protein Size: 776

Molecular Weight: 90 kDa

Gene ID: 8454

NCBI Accession: NM_003592, NP_003583

UniProt: Q13616

Pathways: Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases, Regulation of Cell Size