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- Target See all SPDYC Antibodies
- SPDYC (Speedy Homolog C (SPDYC))
- Binding Specificity
- N-Term
- Reactivity
- Human
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Western Blotting (WB)
- Sequence
- PISISYEMSD SQDPTTSPVV TTQVELGGCS RQGGGNGFLR FRQHQEVQAF
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against SPDYC. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human SPDYC
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SPDYC (Speedy Homolog C (SPDYC))
- Alternative Name
- SPDYC (SPDYC Products)
- Synonyms
- RINGOC antibody, Ringo2 antibody, Speedy antibody, ls26 antibody, ringo antibody, ringo2 antibody, ringo3 antibody, spdy1 antibody, spdya antibody, spdya-A antibody, spy1 antibody, speedy/RINGO cell cycle regulator family member C antibody, speedy/RINGO cell cycle regulator family member C S homeolog antibody, SPDYC antibody, spdyc.S antibody
- Background
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SPDYC promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. It is involved in the spindle-assembly checkpoint. It is required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores and is required for the correct localization of the active form of Aurora B in prometaphase.
Alias Symbols: RINGOC, Ringo2
Protein Size: 293 - Molecular Weight
- 33 kDa
- Gene ID
- 387778
- NCBI Accession
- NM_001008778, NP_001008778
- UniProt
- Q5MJ68
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