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SLX1A/GIYD2 antibody (N-Term)

SLX1B Reactivity: Human, Mouse, Horse, Guinea Pig, Rabbit, Rat, Cow, Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2791914
  • Target See all SLX1A/GIYD2 (SLX1B) Antibodies
    SLX1A/GIYD2 (SLX1B) (SLX1 Structure-Specific Endonuclease Subunit Homolog B (SLX1B))
    Binding Specificity
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Horse, Guinea Pig, Rabbit, Rat, Cow, Dog
    Host
    • 4
    • 3
    Rabbit
    Clonality
    • 7
    Polyclonal
    Conjugate
    • 7
    This SLX1A/GIYD2 antibody is un-conjugated
    Application
    • 7
    • 1
    Western Blotting (WB)
    Sequence
    FFGVYLLYCL NPRYRGRVYV GFTVNTARRV QQHNGGRKKG GAWRTSGRGP
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against SLX1B. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human SLX1B
    Top Product
    Discover our top product SLX1B Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SLX1A/GIYD2 (SLX1B) (SLX1 Structure-Specific Endonuclease Subunit Homolog B (SLX1B))
    Alternative Name
    SLX1B (SLX1B Products)
    Synonyms
    1110030E23Rik antibody, 2410170E21Rik antibody, 4833422P03Rik antibody, AI853643 antibody, Giyd1 antibody, Giyd2 antibody, LRRGT00058 antibody, RGD1311568 antibody, GIYD2 antibody, SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) antibody, SLX1 homolog B, structure-specific endonuclease subunit antibody, Slx1b antibody, SLX1B antibody
    Background
    This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication, this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) gene.
    Protein Interaction Partner: SLX4, THAP11, DUSP10, TUBA1B, LOC344382, EME1, SLX4IP, SLIRP, MUS81, GEMIN6, PAGR1, FKBP10, GEMIN4, DDX20, TIMM17B, PSME3, SLC25A13, HUWE1, PSMD6, CUL1, UQCRC2, SMN1, S100A8, RAN, PSMD11, PSMB5, PSMB3, PSMB2, PSMB1, PSMA7, PSMA6, PSMA5, PSMA4, PSMA3, PSMA
    Protein Size: 275
    Molecular Weight
    30 kDa
    Gene ID
    79008
    UniProt
    Q9BQ83
    Pathways
    DNA Damage Repair
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