PIK3R6 antibody (C-Term)

Catalog No. ABIN2791854

Product Details anti-PIK3R6 Antibody

Target: PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIK3R6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VKSSNLAGKS FSTVTNTFRT NNIQIQSRDQ RLLTLSLDKD DQRTFRDVVR

Predicted Reactivity: Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Pig: 85%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against PIK3R6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PIK3R6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PIK3R6

Target: PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))

Alternative Name: PIK3R6 (PIK3R6 Products)

Synonyms: C17orf38 antibody, HsT41028 antibody, p84 antibody, p84 PIKAP antibody, p87(PIKAP) antibody, p87PIKAP antibody, BB220380 antibody, RGD1560850 antibody, phosphoinositide-3-kinase regulatory subunit 6 antibody, phosphoinositide-3-kinase regulatory subunit 5 antibody, phosphoinositide-3-kinase, regulatory subunit 6 antibody, PIK3R6 antibody, Pik3r6 antibody

Background: Phosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase, regulatory subunit 5 gene which is located adjacent to this gene on chromosome 7. The orthologous protein in the mouse binds to both the catalytic subunit and to G(beta/gamma), and mediates activation of the kinase subunit downstream of G protein-coupled receptors.
Alias Symbols: C17orf38, HsT41028, p84, p87(PIKAP), p87PIKAP
Protein Size: 754

Molecular Weight: 84 kDa

Gene ID: 146850

NCBI Accession: NM_001010855, NP_001010855

UniProt: Q5UE93

Pathways: PI3K-Akt Signaling, Inositol Metabolic Process