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PDZD3 antibody (C-Term)
PDZD3
Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PDZD3 Antibody
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Target
See all PDZD3 Antibodies
PDZD3
(PDZ Domain Containing 3 (PDZD3))
Binding Specificity
All epitopes for PDZD3 antibodies
C-Term
Reactivity
All reactivities for PDZD3 antibodies
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
Host
All hosts for PDZD3 antibodies
Rabbit
Clonality
All clonalities for PDZD3 antibodies
Polyclonal
Conjugate
All conjugates for PDZD3 antibodies
This PDZD3 antibody is un-conjugated
Application
All applications for PDZD3 antibodies
Western Blotting (WB)
Sequence
APLAEGWALP TKPRCLHLEK GPQGFGFLLR EEKGLDGRPG QFLWEVDPGL
Predicted Reactivity
Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 86%
Characteristics
This is a rabbit polyclonal antibody against PDZD3. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human PDZD3
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for PDZD3
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Target
PDZD3
(PDZ Domain Containing 3 (PDZD3))
Alternative Name
PDZD3 (PDZD3 Products )
Synonyms
RGD1559807 antibody, zgc:194812 antibody, IKEPP antibody, NHERF4 antibody, PDZK2 antibody, NaPi-Cap2 antibody, Pdzk2 antibody, PDZ domain containing 3 antibody, PDZ domain containing 3b antibody, Pdzd3 antibody, pdzd3b antibody, PDZD3 antibody
Background
Guanylyl cyclase C (GCC, or GUCY2C, MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR, MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation. Protein Interaction Partner: SPRYD7, ASAP3, SLC41A3, CACNA1S, PTGIR, SLC22A4, SLCO1A2, SLC15A2, SLCO1C1, GUCY2C, SLCO3A1, SLC22A9, SLC22A3, SLC22A5, CFTR, ABCC2, SLC15A1, Protein Size: 571
Molecular Weight
62 kDa
Gene ID
79849
UniProt
Q86UT5
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