MRPL18 antibody (N-Term)

Catalog No. ABIN2791669

Product Details anti-MRPL18 Antibody

Target: MRPL18 (Mitochondrial Ribosomal Protein L18 (MRPL18))

Binding Specificity: N-Term

Reactivity: Human, Dog, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL18 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RNPGCRFAAL STSSEPAAKP EVDPVENEAV APEFTNRNPR NLELLSVARK

Predicted Reactivity: Dog: 93%, Human: 100%, Rabbit: 79%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against MRPL18. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MRPL18

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL18

Target: MRPL18 (Mitochondrial Ribosomal Protein L18 (MRPL18))

Alternative Name: MRPL18 (MRPL18 Products)

Synonyms: L18mt antibody, MRP-L18 antibody, 1010001C05Rik antibody, C79879 antibody, HSPC071 antibody, mitochondrial ribosomal protein L18 antibody, MRPL18 antibody, Mrpl18 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L18P ribosomal protein family. Three polymorphic sites exist in this gene, one of which is three nt in length which causes an extra aa near the N-terminus.
Alias Symbols: L18mt, MRP-L18
Protein Interaction Partner: NPM1, C1QBP, UBC, Ybx1, ICT1,
Protein Size: 180

Molecular Weight: 20 kDa

Gene ID: 29074

NCBI Accession: NM_014161, NP_054880

UniProt: Q9H0U6