LAGE3 antibody (N-Term)

Catalog No. ABIN2791636

Product Details anti-LAGE3 Antibody

Target: LAGE3 (L Antigen Family, Member 3 (LAGE3))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAGE3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MRDADADAGG GADGGDGRGG HSCRGGVDTA AAPAGGAPPA HAPGPGRDAA

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against LAGE3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human LAGE3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LAGE3

Target: LAGE3 (L Antigen Family, Member 3 (LAGE3))

Alternative Name: LAGE3 (LAGE3 Products)

Synonyms: CVG5 antibody, ESO3 antibody, ITBA2 antibody, DXS9879E antibody, DXS9951E antibody, 1110049G11Rik antibody, Eso3 antibody, Itba2 antibody, L antigen family member 3 antibody, L antigen family, member 3 antibody, LAGE3 antibody, Lage3 antibody

Background: This gene belongs to the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activated in a wide range of human tumors, this gene is ubiquitously expressed in somatic tissues. The latter, combined with the finding that it is highly conserved in mouse and rat, suggests that the encoded protein is functionally important. An intronless pseudogene with high sequence similarity to this gene is located on chromosome 9.
Alias Symbols: CVG5, DXS9879E, DXS9951E, ESO3, ITBA2
Protein Interaction Partner: KRT40, PDE9A, UBC, CNN2, TP53RK, VCPKMT, RNF114, RPAP1, PTPN23, SEPHS2, OGFR, MAGED2, AHCYL1, SSSCA1, USP34, PUM1, SNRPF, RAB5B, PTMS, PLP2, MT1A, RNF214, TOM1L2, MCFD2, ZFYVE19, GINS4, NDRG3, C14orf142, CAND1, OSGEP, TPRKB, PRAME, CUL2, TCEB2, TCEB1,
Protein Size: 143

Molecular Weight: 14 kDa

Gene ID: 8270

NCBI Accession: NM_006014, NP_006005

UniProt: Q14657