Keratin 78 antibody (Middle Region)

Catalog No. ABIN2791631

Product Details anti-Keratin 78 Antibody

Target: Keratin 78 (KRT78)

Binding Specificity: Middle Region

Reactivity: Human, Cow, Dog, Guinea Pig, Mouse, Rabbit, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Keratin 78 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CRDQEEEYKS KYEEEAHRRA TLENDFVVLK KDVDGVFLSK MELEGKLEAL

Predicted Reactivity: Cow: 83%, Dog: 85%, Guinea Pig: 80%, Human: 100%, Mouse: 80%, Pig: 90%, Rabbit: 92%, Rat: 80%

Characteristics: This is a rabbit polyclonal antibody against KRT78. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human KRT78

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Keratin 78

Target: Keratin 78 (KRT78)

Alternative Name: KRT78 (KRT78 Products)

Synonyms: K5B antibody, Kb40 antibody, keratin 78 antibody, KRT78 antibody

Background: This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified.
Alias Symbols: K5B, Kb40
Protein Interaction Partner: MDM2, Nphp4, IQCB1, UBC, CRK, COPS5, CUL2, CUL3, UCHL5, SIRT2,
Protein Size: 520

Molecular Weight: 57 kDa

Gene ID: 196374

NCBI Accession: NM_173352, NP_775487

UniProt: Q8N1N4