GRAP antibody (N-Term)

Catalog No. ABIN2791566

Product Details anti-GRAP Antibody

Target: GRAP (GRB2-Related Adaptor Protein (GRAP))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Rabbit, Goat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRAP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SDELAFNKGD TLKILNMEDD QNWYKAELRG VEGFIPKNYI RVKPHPWYSG

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against GRAP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GRAP

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GRAP

Target: GRAP (GRB2-Related Adaptor Protein (GRAP))

Alternative Name: GRAP (GRAP Products)

Synonyms: 8430435N19Rik antibody, BB233594 antibody, GRAP antibody, grap antibody, zgc:110202 antibody, MGC109892 antibody, si:dkeyp-9d4.1 antibody, Grap antibody, GRB2-related adaptor protein antibody, GRB2-related adapter protein antibody, GRB2-related adaptor protein a antibody, GRB2-related adaptor protein b antibody, GRAP antibody, Grap antibody, LOC489534 antibody, grapa antibody, grapb antibody, LOC100727005 antibody

Background: This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.
Alias Symbols: -
Protein Interaction Partner: TRIM21, RBPMS, UBC, ARHGAP32, KHDRBS1, LAT, SHC1, SOS1, PLCG1, KIT, LCK, FYN, FASLG, EPOR, GAB2,
Protein Size: 217

Molecular Weight: 25 kDa

Gene ID: 10750

NCBI Accession: NM_006613, NP_006604

UniProt: Q13588