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C1orf86 antibody (C-Term)

C1ORF86 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2791345
  • Target See all C1orf86 (C1ORF86) products
    C1orf86 (C1ORF86) (Chromosome 1 Open Reading Frame 86 (C1ORF86))
    Binding Specificity
    • 4
    • 1
    C-Term
    Reactivity
    • 5
    • 1
    Human
    Host
    • 6
    Rabbit
    Clonality
    • 6
    Polyclonal
    Conjugate
    • 3
    • 1
    • 1
    • 1
    This C1orf86 antibody is un-conjugated
    Application
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    ARSLPQRPAP DPCRAPRVEQ QPSVEGAAAL RSCPMCQKEF APRLTQLDVD
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against C1orf86. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human C1orf86
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 180 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    C1orf86 (C1ORF86) (Chromosome 1 Open Reading Frame 86 (C1ORF86))
    Alternative Name
    C1orf86 (C1ORF86 Products)
    Synonyms
    FAAP20 antibody, FP7162 antibody, Fanconi anemia core complex associated protein 20 antibody, FAAP20 antibody
    Background
    C1orf86 is a component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. It promotes translesion synthesis via interaction with REV1.
    Alias Symbols: FP7162
    Protein Interaction Partner: FANCL, FANCA, UBC, FANCC, APITD1, C19orf40, C17orf70, FANCM, REV1, FANCG, FANCF, FANCB, FANCE, ELAVL1,
    Protein Size: 180
    Molecular Weight
    19 kDa
    Gene ID
    199990
    NCBI Accession
    NM_182533, NP_872339
    UniProt
    Q6NZ36
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