BEAN1 antibody (C-Term)
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- Target See all BEAN1 Antibodies
- BEAN1 (Brain Expressed, Associated with NEDD4, 1 (BEAN1))
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Binding Specificity
- C-Term
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BEAN1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- TDAPPPYSLT DSCPTLDGTS DSGSGHSPGR HQQEQRTPAQ GGLHTVSMDT
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against BEAN1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human BEAN1
- Top Product
- Discover our top product BEAN1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 259 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- BEAN1 (Brain Expressed, Associated with NEDD4, 1 (BEAN1))
- Alternative Name
- BEAN1 (BEAN1 Products)
- Synonyms
- BEAN antibody, SCA31 antibody, Bean antibody, brain expressed associated with NEDD4 1 antibody, brain expressed, associated with Nedd4, 1 antibody, BEAN1 antibody, Bean1 antibody
- Background
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The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: BEAN, SCA31
Protein Interaction Partner: BAG3, Nedd4,
Protein Size: 259 - Molecular Weight
- 28 kDa
- Gene ID
- 146227
- NCBI Accession
- NM_001178020, NP_001171491
- UniProt
- Q3B7T3
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