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KNSTRN antibody (Middle Region)

KNSTRN Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2791244
  • Target See all KNSTRN Antibodies
    KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))
    Binding Specificity
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae
    Host
    • 5
    Rabbit
    Clonality
    • 5
    Polyclonal
    Conjugate
    • 5
    This KNSTRN antibody is un-conjugated
    Application
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    TDTATRRNVR KGYKPLSKQK SEEELKDKNQ LLEAVNKQLH QKLTETQGEL
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 79%, Yeast: 82%
    Characteristics
    This is a rabbit polyclonal antibody against C15orf23. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of Human C15orf23
    Top Product
    Discover our top product KNSTRN Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 316 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))
    Alternative Name
    C15orf23 (KNSTRN Products)
    Synonyms
    1700025D04Rik antibody, C15orf23 antibody, D2Ertd750e antibody, SKAP antibody, Traf4af1 antibody, TRAF4AF1 antibody, kinetochore-localized astrin/SPAG5 binding antibody, kinetochore localized astrin/SPAG5 binding protein antibody, kinetochore-localized astrin/SPAG5 binding protein antibody, Knstrn antibody, KNSTRN antibody
    Background
    C15orf23 is an essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. It promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments.
    Alias Symbols: SKAP, TRAF4AF1, C15orf23
    Protein Interaction Partner: UBC, CLU, CHMP1B, MAPK6, Cep152, Cep55, Dynll1, Mad2l1, Spag5, Knstrn, Plk1, MPHOSPH6, MPP6,
    Protein Size: 316
    Molecular Weight
    35 kDa
    Gene ID
    90417
    NCBI Accession
    NM_033286, NP_150628
    UniProt
    Q9Y448
    Pathways
    M Phase
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