AP1AR antibody (C-Term)

Catalog No. ABIN2791123

Product Details anti-AP1AR Antibody

Target: AP1AR (Adaptor-Related Protein Complex 1 Associated Regulatory Protein (AP1AR))

Binding Specificity: C-Term

Reactivity: Human, Cow, Dog, Horse, Mouse, Pig, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP1AR antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DSTSLDLEWE DEEGMNRMLP MRERSKTEED ILRAALKYSN KKTGSNPTSA

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 83%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 77%

Characteristics: This is a rabbit polyclonal antibody against AP1AR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human AP1AR

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 302 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AP1AR

Target: AP1AR (Adaptor-Related Protein Complex 1 Associated Regulatory Protein (AP1AR))

Alternative Name: AP1AR (AP1AR Products)

Synonyms: 2C18 antibody, C4orf16 antibody, GBAR antibody, gamma-BAR antibody, adaptor related protein complex 1 associated regulatory protein antibody, AP1AR antibody

Background: AP1AR is necessary for AP-1 dependent transport between the trans-Golgi network and endosomes. It regulates the membrane association of AP1G1/Gamma1-adaptin, one of the subunits of the AP-1 adapter complex. The direct interaction with AP1G1/Gamma1-adaptin attenuates the release of the AP-1 complex from membranes.
Alias Symbols: 2C18, C4orf16, GBAR, gamma-BAR
Protein Interaction Partner: UBC, ELAVL1, GGA1, AP1G1,
Protein Size: 302

Molecular Weight: 34 kDa

Gene ID: 55435

NCBI Accession: NM_018569, NP_061039

UniProt: Q63HQ0