DENND1C antibody (C-Term)
DENND1C
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
1 image
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- Target See all DENND1C Antibodies
- DENND1C (DENN/MADD Domain Containing 1C (DENND1C))
- Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DENND1C antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PSSLEDPRAR PPKALLAERA HLQPREEPGA LNSPATPTSN CQKSQPSSRP
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against DENND1C. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human DENND1C
- Top Product
- Discover our top product DENND1C Primary Antibody
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anti-DENN/MADD Domain Containing 1C (DENND1C) (AA 601-801) antibody
DENND1C Reactivity: Human ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 801 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- DENND1C (DENN/MADD Domain Containing 1C (DENND1C))
- Alternative Name
- DENND1C (DENND1C Products)
- Synonyms
- FAM31C antibody, 4432409M07Rik antibody, DENN/MADD domain containing 1C L homeolog antibody, DENN/MADD domain containing 1C antibody, DENN domain containing 1C antibody, dennd1c.L antibody, DENND1C antibody, Dennd1c antibody
- Background
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Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.
Alias Symbols: FAM31C
Protein Interaction Partner: APP, ELAVL1,
Protein Size: 801 - Molecular Weight
- 87 kDa
- Gene ID
- 79958
- NCBI Accession
- NM_024898, NP_079174
- UniProt
- Q8IV53
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