CES4A antibody (C-Term)

Catalog No. ABIN2790977

Product Details anti-CES4A Antibody

Target: CES4A (Carboxylesterase 4A (CES4A))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CES4A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KYWANFARTG NPNDGNLPCW PRYNKDEKYL QLDFTTRVGM KLKEKKMAFW

Predicted Reactivity: Cow: 100%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against CES4A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human CES4A

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CES4A

Target: CES4A (Carboxylesterase 4A (CES4A))

Alternative Name: CES4A (CES4A Products)

Synonyms: CES6 antibody, CES8 antibody, Ces8 antibody, RGD1307418 antibody, CES4A antibody, carboxylesterase 4A antibody, CES4A antibody, Ces4a antibody, LOC454151 antibody, LOC102149227 antibody

Background: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They also participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene, also called CES6, encodes a secreted enzyme, and may play a role in the detoxification of drugs and xenobiotics in neural and other tissues of the body and in the cerebrospinal fluid. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature and/or biological validity of some variants have not been determined.
Alias Symbols: CES6, CES8
Protein Size: 514

Molecular Weight: 56 kDa

Gene ID: 283848

NCBI Accession: NM_001190201, NP_001177130

UniProt: Q5XG92