C12orf65 antibody (C-Term)

Catalog No. ABIN2790950

Product Details anti-C12orf65 Antibody

Target: C12orf65 (Chromosome 12 Open Reading Frame 65 (C12orf65))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Pig, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C12orf65 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HIPSGIVVKC HQTRSVDQNR KLARKILQEK VDVFYNGENS PVHKEKREAA

Predicted Reactivity: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against C12orf65. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human C12orf65

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 166 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for C12orf65

Target: C12orf65 (Chromosome 12 Open Reading Frame 65 (C12orf65))

Alternative Name: C12orf65 (C12orf65 Products)

Synonyms: COXPD7 antibody, SPG55 antibody, chromosome 12 open reading frame 65 antibody, C12orf65 antibody

Background: This nuclear gene encodes a mitochondrial matrix protein that appears to contribute to peptide chain termination in the mitochondrial translation machinery. Two different 1 bp deletions (resulting in the same premature stop codon)result in decreased mitochondrial translation, decreased levels of oxidative phosphorylation complexes and encepthalomyopathy. Alternative splicing results in multiple transcript variants.
Alias Symbols: COXPD7
Protein Interaction Partner: UBC, CDK2, APP,
Protein Size: 166

Molecular Weight: 18 kDa

Gene ID: 91574

NCBI Accession: NM_152269, NP_689482

UniProt: Q9H3J6