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PARPBP antibody (C-Term)
PARPBP
Reactivity: Human, Horse, Rabbit, Pig, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PARPBP Antibody
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Target
See all PARPBP Antibodies
PARPBP
(PARP1 Binding Protein (PARPBP))
Binding Specificity
All epitopes for PARPBP antibodies
C-Term
Reactivity
Human, Horse, Rabbit, Pig, Rat
Host
All hosts for PARPBP antibodies
Rabbit
Clonality
All clonalities for PARPBP antibodies
Polyclonal
Conjugate
All conjugates for PARPBP antibodies
This PARPBP antibody is un-conjugated
Application
All applications for PARPBP antibodies
Western Blotting (WB)
Sequence
YMENDLSEGV NPSVGRSTIG TSFGNVHLDR SKNEKVSRKS TSQTGNKSSK
Predicted Reactivity
Horse: 85%, Human: 100%, Pig: 92%, Rabbit: 86%, Rat: 93%
Characteristics
This is a rabbit polyclonal antibody against PARPBP. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human PARPBP
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for PARPBP
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Target
PARPBP
(PARP1 Binding Protein (PARPBP))
Alternative Name
PARPBP (PARPBP Products )
Background
PARPBP is required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. PARPBP antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. It binds single-strand DNA and poly(A) homopolymers and positively regulate the poly(ADP-ribosyl)ation activity of PARP1, however such function may be indirect. Protein Interaction Partner: UBC, Protein Size: 294
Molecular Weight
32 kDa
Gene ID
55010
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