ANAPC15 antibody (N-Term)

Catalog No. ABIN2790945

Product Details anti-ANAPC15 Antibody

Target: ANAPC15 (Anaphase Promoting Complex Subunit 15 (ANAPC15))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANAPC15 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EETELQQQEQ QHQAWLQSIA EKDNNLVPIG KPASEHYDDE EEEDDEDDED

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against ANAPC15. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ANAPC15

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 121 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ANAPC15

Target: ANAPC15 (Anaphase Promoting Complex Subunit 15 (ANAPC15))

Alternative Name: ANAPC15 (ANAPC15 Products)

Synonyms: APC15 antibody, C11orf51 antibody, C15H11orf51 antibody, anaphase promoting complex subunit 15 antibody, ANAPC15 antibody

Background: ANAPC15 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20.
Alias Symbols: APC15, C11orf51
Protein Interaction Partner: ANAPC4, CDC26, ANAPC1, ANAPC7, ANAPC5, ANAPC2, ANAPC10, CDC16, CDC23, CDC27, CDC20,
Protein Size: 121

Molecular Weight: 13 kDa

Gene ID: 25906

NCBI Accession: NM_014042, NP_054761

UniProt: P60006