YTHDF2 antibody (C-Term)
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- Target See all YTHDF2 Antibodies
- YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))
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Binding Specificity
- C-Term
- Reactivity
- Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Goat, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This YTHDF2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- WSQDKWKGRF DVRWIFVKDV PNSQLRHIRL ENNENKPVTN SRDTQEVPLE
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against YTHDF2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human YTHDF2
- Top Product
- Discover our top product YTHDF2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 529 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))
- Alternative Name
- YTHDF2 (YTHDF2 Products)
- Synonyms
- MGC82537 antibody, HGRG8 antibody, NY-REN-2 antibody, YTH N(6)-methyladenosine RNA binding protein 2 L homeolog antibody, YTH N6-methyladenosine RNA binding protein 2 antibody, ythdf2.L antibody, YTHDF2 antibody
- Background
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This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosme 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene.
Alias Symbols: HGRG8, NY-REN-2
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, RNF2, BMI1, EIF3H, EIF3A, FBXO6, TARDBP, HIPK4, VCAM1, FN1, EPAS1, ESR1, APP, SMAD3, CAND1, CUL3, ELAVL1, POT1, MEPCE, HNRNPH1, HNRNPA1,
Protein Size: 529 - Molecular Weight
- 58 kDa
- Gene ID
- 51441
- NCBI Accession
- NM_016258, NP_057342
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