Frmpd2 antibody, Gm1582 antibody, ENSMUSG00000071536 antibody, FRMPD2 antibody, PDZD5C antibody, PDZK4 antibody, PDZK5C antibody, FERM and PDZ domain containing 2 antibody, putative protein FRMPD2-like antibody, FERM and PDZ domain-containing protein 2 antibody, Frmpd2 antibody, FRMPD2 antibody, LOC100051923 antibody, LOC100348282 antibody, LOC100548446 antibody
Background
This gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene is full-length and is in the telomeric duplicated region. Two other more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full-length gene appears to function in the establishment and maintenance of cell polarization. The protein is recruited to cell-cell junctions in an E-cadherin-dependent manner, and is selectively localized at the basolateral membrane in polarized epithelial cells. Alternative splicing results in multiple transcript variants. Protein Size: 392