ATPBD3 antibody (C-Term)
-
- Target See all ATPBD3 (CTU1) Antibodies
- ATPBD3 (CTU1) (Cytosolic Thiouridylase Subunit 1 Homolog (CTU1))
-
Binding Specificity
- C-Term
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This ATPBD3 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- ALASRALCQA CALLDGLNRG RPRLAIGKGR RGLDEEATPG TPGDPARPPA
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against CTU1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CTU1
- Top Product
- Discover our top product CTU1 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 348 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- ATPBD3 (CTU1) (Cytosolic Thiouridylase Subunit 1 Homolog (CTU1))
- Alternative Name
- CTU1 (CTU1 Products)
- Synonyms
- ATPBD3 antibody, NCS6 antibody, atpbd3 antibody, ncs6 antibody, Atpbd3 antibody, RGD1308740 antibody, BC005752 antibody, zgc:55395 antibody, cytosolic thiouridylase subunit 1 antibody, cytosolic thiouridylase subunit 1 L homeolog antibody, cytosolic thiouridylase subunit 1 homolog (S. pombe) antibody, CTU1 antibody, ctu1.L antibody, Ctu1 antibody, ctu1 antibody
- Background
-
CTU1 plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). CTU1 directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
Alias Symbols: ATPBD3, NCS6
Protein Interaction Partner: FAM96B, CIAO1, MMS19, CTU2, URM1, HSPA4,
Protein Size: 348 - Molecular Weight
- 38 kDa
- Gene ID
- 90353
- NCBI Accession
- NM_145232, NP_660275
- UniProt
- Q7Z7A3
-