CDC42SE2 antibody (Middle Region)

Catalog No. ABIN2790743

Product Details anti-CDC42SE2 Antibody

Target: CDC42SE2 (CDC42 Small Effector 2 (CDC42SE2))

Binding Specificity: Middle Region

Reactivity: Human, Guinea Pig, Horse, Mouse, Rabbit, Cow, Rat, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC42SE2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NFVHTAHVGS GDLFSGMNSV SSIQNQMQSK GGYGGGMPAN VQMQLVDTKA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CDC42SE2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human CDC42SE2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 84 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDC42SE2

Target: CDC42SE2 (CDC42 Small Effector 2 (CDC42SE2))

Alternative Name: CDC42SE2 (CDC42SE2 Products)

Synonyms: SPEC2 antibody, 2810404F18Rik antibody, AA408783 antibody, AA536669 antibody, RGD1563924 antibody, cdc42se2 antibody, CDC42 small effector 2 antibody, CDC42SE2 antibody, Cdc42se2 antibody, cdc42se2 antibody

Background: CDC42SE2 is probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. It alters CDC42-induced cell shape changes. In activated T-cells, CDC42SE2 may play a role in CDC42-mediated F-actin accumulation at the immunological synapse and may play a role in early contractile events in phagocytosis in macrophages.
Alias Symbols: FLJ21967, SPEC2
Protein Interaction Partner: UBC, ELAVL1, RAC1, CDC42,
Protein Size: 84

Molecular Weight: 9 kDa

Gene ID: 56990

NCBI Accession: NM_020240, NP_064625

UniProt: Q9NRR3