NADSYN1 antibody (C-Term)

Catalog No. ABIN2790661

Product Details anti-NADSYN1 Antibody

Target: NADSYN1 (NAD Synthetase 1 (NADSYN1))

Binding Specificity: C-Term

Reactivity: Human, Rat, Cow, Dog, Guinea Pig, Goat, Horse, Mouse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NADSYN1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PAYHAENYSP EDNRFDLRPF LYNTSWPWQF RCIENQVLQL ERAEPQSLDG

Predicted Reactivity: Cow: 86%, Dog: 86%, Goat: 85%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rat: 93%, Yeast: 93%

Characteristics: This is a rabbit polyclonal antibody against NADSYN1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NADSYN1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 706 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NADSYN1 antibody (ABIN2790661)

Yue, Chen, Xie, Hao, Guo, Sun, Jia, Zhang, Zhou, Zhong: "Activation of PPARα-catalase pathway reverses alcoholic liver injury via upregulating NAD synthesis and accelerating alcohol clearance." in: Free radical biology & medicine, Vol. 174, pp. 249-263, (2021) (PubMed).

Target Details for NADSYN1

Target: NADSYN1 (NAD Synthetase 1 (NADSYN1))

Alternative Name: NADSYN1 (NADSYN1 Products)

Synonyms: NADSYN1 antibody, zgc:165489 antibody, 9130012B15Rik antibody, NAD synthetase 1 antibody, NADSYN1 antibody, nadsyn1 antibody, PTRG_02392 antibody, Nadsyn1 antibody

Background: Nicotinamide adenine dinucleotide (NAD) is a coenzyme in metabolic redox reactions, a precursor for several cell signaling molecules, and a substrate for protein posttranslational modifications. NAD synthetase (EC 6.3.5.1) catalyzes the final step in the biosynthesis of NAD from nicotinic acid adenine dinucleotide (NaAD).
Alias Symbols: FLJ10631, FLJ36703, FLJ40627
Protein Interaction Partner: MYO15B, STUB1, AIP, UPF1, UBC, UBD, NADSYN1, CUTC,
Protein Size: 706

Molecular Weight: 78 kDa

Gene ID: 55191

NCBI Accession: NM_018161, NP_060631

UniProt: Q6IA69