MRPL36 antibody (C-Term)

Catalog No. ABIN2790654

Product Details anti-MRPL36 Antibody

Target: MRPL36 (Mitochondrial Ribosomal Protein L36 (MRPL36))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Pig, Rabbit, Rat, Cow, Saccharomyces cerevisiae, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL36 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PGLLPHLLPA LGFKNKTVLK KRCKDCYLVK RRGRWYVYCK THPRHKQRQM

Predicted Reactivity: Cow: 79%, Dog: 82%, Guinea Pig: 75%, Horse: 86%, Human: 100%, Mouse: 83%, Pig: 79%, Rabbit: 79%, Rat: 83%, Yeast: 77%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against MRPL36. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MRPL36

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 103 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL36

Target: MRPL36 (Mitochondrial Ribosomal Protein L36 (MRPL36))

Alternative Name: MRPL36 (MRPL36 Products)

Synonyms: DDBDRAFT_0187049 antibody, DDBDRAFT_0232367 antibody, DDB_0187049 antibody, DDB_0232367 antibody, rpmj antibody, brip1 antibody, l36mt antibody, prpl36 antibody, BRIP1 antibody, L36mt antibody, MRP-L36 antibody, PRPL36 antibody, RPMJ antibody, AI646041 antibody, si:dkey-261i16.3 antibody, DEAD/DEAH box helicase antibody, mitochondrial ribosomal protein L36 antibody, BRIP1 antibody, mrpl36 antibody, MRPL36 antibody, Mrpl36 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 2p.
Alias Symbols: BRIP1, L36mt, MGC104245, MRP-L36, PRPL36, RPMJ
Protein Interaction Partner: UBC, RRAS, BRCA1,
Protein Size: 103

Molecular Weight: 11 kDa

Gene ID: 64979

NCBI Accession: NM_032479, NP_115868

UniProt: Q9P0J6