MEPCE antibody (Middle Region)

Catalog No. ABIN2790651

Product Details anti-MEPCE Antibody

Target: MEPCE (Methylphosphate Capping Enzyme (MEPCE))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEPCE antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HRHRGQHHQQ QQAAGGSESH PVPPTAPLTP LLHGEGASQQ PRHRGQNRDA

Predicted Reactivity: Dog: 79%, Guinea Pig: 86%, Human: 100%, Rabbit: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against MEPCE. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human MEPCE

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 689 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MEPCE

Target: MEPCE (Methylphosphate Capping Enzyme (MEPCE))

Alternative Name: MEPCE (MEPCE Products)

Background: MEPCE is a S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.
Alias Symbols: BCDIN3, FLJ20257
Protein Interaction Partner: CDK9, LIN28A, LARP7, SNRPG, SNRPF, SNRPB2, SNRPB, CTSA, NEDD8, SART3, PRPF3, SUMO1, UBC, GLB1, BMI1, PRPF19, SOX2, tat, BARD1, CAND1, CUL3, ISG15, CCT2, CCT4, ANP32B, NOP56, DDX17, SYNCRIP, PPIH, HNRNPR, ALYREF, TRIM28, HNRNPA3P1, USP15, CKAP5, MATR3, AKA
Protein Size: 689

Molecular Weight: 76 kDa

Gene ID: 56257

NCBI Accession: NM_019606, NP_062552

UniProt: Q7L2J0

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection