NKAP antibody (C-Term)

Catalog No. ABIN2790485

Product Details anti-NKAP Antibody

Target: NKAP (NFKB Activating Protein (NKAP))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKAP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EAVRLRKENQ IYSADEKRAL ASFNQEERRK RENKILASFR EMVYRKTKGK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against NKAP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NKAP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 415 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NKAP

Target: NKAP (NFKB Activating Protein (NKAP))

Alternative Name: NKAP (NKAP Products)

Background: This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.
Alias Symbols: FLJ22626
Protein Interaction Partner: UBC, SRPK1, CSNK2A2, TTC14, FRA10AC1, NKAP, PRPF40A, RBMX2, DDX41, RBM39, PPIG, BUB3, PRPF3, U2AF1, PCBP2, DHX15, DHX8, CUL5, SUMO2, LUC7L2, CEP70, THAP1, FAM124A,
Protein Size: 415

Molecular Weight: 46 kDa

Gene ID: 79576

NCBI Accession: NM_024528, NP_078804

UniProt: Q8N5F7

Pathways: Stem Cell Maintenance, The Global Phosphorylation Landscape of SARS-CoV-2 Infection