IDH3B antibody (N-Term)
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- Target See all IDH3B Antibodies
- IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IDH3B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- SEVQNMASEE KLEQVLSSMK ENKVAIIGKI HTPMEYKGEL ASYDMRLRRK
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against IDH3B. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human IDH3B
- Top Product
- Discover our top product IDH3B Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 385 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))
- Alternative Name
- IDH3B (IDH3B Products)
- Synonyms
- H-IDHB antibody, RP46 antibody, C78231 antibody, zgc:86647 antibody, MGC79028 antibody, IDH1 antibody, IDH3 antibody, isocitrate dehydrogenase 3 (NAD(+)) beta antibody, isocitrate dehydrogenase 3 (NAD+) beta antibody, isocitrate dehydrogenase 3 (NAD+) beta S homeolog antibody, IDH3B antibody, Idh3B antibody, Idh3b antibody, idh3b antibody, idh3b.S antibody
- Background
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Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.
Alias Symbols: FLJ11043, H-IDHB, MGC903, RP46
Protein Interaction Partner: TP53, SUMO2, ADRB2, MMS19, ATXN2, UBC, EBNA-LP, MAPK6, MYC, RAB35, PRMT1, IDH3A, IDH3G,
Protein Size: 385 - Molecular Weight
- 42 kDa
- Gene ID
- 3420
- NCBI Accession
- NM_006899, NP_008830
- UniProt
- O43837
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