Keratin 85 antibody (C-Term)

Catalog No. ABIN2790419

Product Details anti-Keratin 85 Antibody

Target: Keratin 85 (KRT85)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Cow, Dog, Horse, Pig, Rabbit, Rat, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Keratin 85 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DVASRSRAEA ESWYRSKCEE MKATVIRHGE TLRRTKEEIN ELNRMIQRLT

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against KRT85. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human KRT85

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Keratin 85

Target: Keratin 85 (KRT85)

Alternative Name: KRT85 (KRT85 Products)

Synonyms: Kb25 antibody, ECTD4 antibody, HB5 antibody, Hb-5 antibody, KRTHB5 antibody, hHb5 antibody, AA589597 antibody, BB007925 antibody, Hb5 antibody, Krt2-18 antibody, keratin 85 antibody, keratin, type II cuticular Hb5 antibody, keratin, type II microfibrillar, component 5-like antibody, Krt85 antibody, KRT85 antibody, LOC100089219 antibody, LOC100141295 antibody, LOC100466881 antibody, LOC100524022 antibody

Background: The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5.
Alias Symbols: HB5, Hb-5, KRTHB5, hHb5
Protein Interaction Partner: UBC, GRB2, EPS15, CUL3, CUL4B, ATG10, ATG3, MLST8, OTUD4, USPL1, USP15, USP8, ALOX12, LYAR, PLEKHB2, TWF2, YWHAG, DLG3, CDC25B, CDC20,
Protein Size: 507

Molecular Weight: 55 kDa

Gene ID: 3891

NCBI Accession: NM_002283, NP_002274

UniProt: P78386