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RIN2 antibody (N-Term)

RIN2 Reactivity: Human, Mouse, Cow, Horse, Pig, Rat, Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2790373
  • Target See all RIN2 Antibodies
    RIN2 (Ras and Rab Interactor 2 (RIN2))
    Binding Specificity
    • 3
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Cow, Horse, Pig, Rat, Dog
    Host
    • 4
    • 4
    Rabbit
    Clonality
    • 5
    • 3
    Polyclonal
    Conjugate
    • 8
    This RIN2 antibody is un-conjugated
    Application
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    RTDVNLENGL EPAETHSMVR HKDGGYSEEE DVKTCARDSG YDSLSNRLSI
    Predicted Reactivity
    Cow: 80%, Dog: 80%, Horse: 80%, Human: 100%, Mouse: 83%, Pig: 80%, Rat: 83%
    Characteristics
    This is a rabbit polyclonal antibody against RIN2. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of human RIN2
    Top Product
    Discover our top product RIN2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    RIN2 (Ras and Rab Interactor 2 (RIN2))
    Alternative Name
    RIN2 (RIN2 Products)
    Synonyms
    RIN2 antibody, RINL antibody, rassf4 antibody, MACS antibody, RASSF4 antibody, 2010003K16Rik antibody, 4632403N06Rik antibody, AW821980 antibody, Ras and Rab interactor 2 antibody, Rin2 antibody, RIN2 antibody, rin2 antibody
    Background
    The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.
    Alias Symbols: MACS, RASSF4
    Protein Size: 462
    Molecular Weight
    50 kDa
    Gene ID
    54453
    NCBI Accession
    NM_001242581, NP_001229510
    UniProt
    Q8WYP3
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