Calpain 8 antibody (Middle Region)

Catalog No. ABIN2790353

Product Details anti-Calpain 8 Antibody

Target: Calpain 8 (CAPN8)

Binding Specificity: Middle Region

Reactivity: Human, Rat, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calpain 8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KLIRLRNPWG EVEWSGAWSD DAPEWNHIDP RRKEELDKKV EDGEFWMSLS

Predicted Reactivity: Guinea Pig: 79%, Horse: 79%, Human: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CAPN8. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human CAPN8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 703 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Calpain 8

Target: Calpain 8 (CAPN8)

Alternative Name: CAPN8 (CAPN8 Products)

Synonyms: nCL-2 antibody, nCL-2' antibody, CL-2' antibody, Cls4 antibody, calpain 8 antibody, CAPN8 antibody, Capn8 antibody

Background: CAPN8 is a calcium-regulated non-lysosomal thiol-protease. CAPN8 is involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. CAPN8 proteolytically cleaves the beta-subunit of coatomer complex.
Alias Symbols: nCL-2
Protein Size: 703

Molecular Weight: 77 kDa

Gene ID: 388743

NCBI Accession: NM_001143962, NP_001137434

UniProt: A6NHC0